Vaginal misoprostol administered 1, 2, or 3 days after mifepristone for early medical abortion: a randomized trial

EA Schaff, SL Fielding, C Westhoff, C Ellertson… - Jama, 2000 - jamanetwork.com
ContextThe conventional timing of misoprostol administration after mifepristone for medical
abortion is 2 days, but more flexible intervals, which may make the regimen more
convenient, have not been studied. ObjectiveTo determine whether vaginal misoprostol
administered 1, 2, or 3 days after mifepristone influences safety or effectiveness for abortion
at up to 56 days' gestation. DesignProspective, randomized, open-label trial conducted from
March 1998 to June 1999. SettingSixteen US primary care and referral abortion facilities …
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